I've developed these for outdoor/daylight shots, but they seem to be work as a good starting point for indoor shots around my house, after a white balance adjustment.
If you want to try these settings you can download the file here and unzip it. You'll need to move it to the user presets folder which on a mac is at (your home directory)/Library/Application Support/Adobe/Lightroom/Develop Presets/User Presets (and i think would be somewhere within the application data folder on windows), and then restart Lightroom.
Here's a sample (click thumbnail for 640x428 version). The only processing (other than application of the preset) done here was exporting from lightroom as small jpegs.
as imported:
this one was cropped somewhat then exported as above...
as imported:
There you go. You should of course develop your own, but this might provide you with a starting point. If you want to share your settings with the world let me know and I'll post 'em here (I can host the files too if you need).
later...josh